The main purpose of the game is to remove all cards from the table, assembling them in the tableau before removing them. Initially, 54 cards are dealt to the tableau in ten piles, face down except for the top cards. The tableau piles build down by rank, and in-suit sequences can be moved together. The 50 remaining cards can be dealt to the tableau ten at a time when none of the piles are empty.

A typical Spider layout requires the use of two decks. The Tableau consists of 10 stacks, with 6 cards in the first 4 stacks, with the 6th card face up, and 5 cards in the remaining 6 stacks, with the 5th card face up. Each time the stock is used it deals out one card to each stack